Adenoid Cystic Carcinoma:  Lung

Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer of the head and neck comprising
approximately 3-5% of all salivary tumors.  ACC may also arise in other primary sites, such as the
breast, prostate, lung, and other organs.  ACC is slow growing and tends to have a high recurrence
rate with metastasizes to the lung and bone.  Patients diagnosed with ACC generally have a poor
prognosis.

Clinical History/Findings

55 y/o male with multiple lung nodules. Patient has history of right maxillary sinus and orbital masses.

Specimen Type

A CT guided fine needle aspiration biopsy (FNAB) and biopsy of a RUL lung mass was performed.

Cytologic Findings




































Cytologic Diagnosis:  Adenoid Cystic Carcinoma metastatic from the right maxillary  
                                   sinus.

Submitted by:
Joe M. Martinez BS, SCT (ASCP)
Cytopathology Supervisor
Audie Murphy VA Hospital
San Antonio, TX
Return to Case Studies
Slide 1: Adenoid cystic carcinoma.
Extracellular hyaline globules.
Slide 2:   Maliganant cells arranged
around pseudoglandular or microcystic
spaces which appear clear in H& E.
The Texas Society of Cytology