Adenoid Cystic Carcinoma: Lung
Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer of the head and neck comprising
approximately 3-5% of all salivary tumors. ACC may also arise in other primary sites, such as the
breast, prostate, lung, and other organs. ACC is slow growing and tends to have a high recurrence
rate with metastasizes to the lung and bone. Patients diagnosed with ACC generally have a poor
prognosis.
Clinical History/Findings
55 y/o male with multiple lung nodules. Patient has history of right maxillary sinus and orbital masses.
Specimen Type
A CT guided fine needle aspiration biopsy (FNAB) and biopsy of a RUL lung mass was performed.
Cytologic Findings
Cytologic Diagnosis: Adenoid Cystic Carcinoma metastatic from the right maxillary
sinus.
Submitted by:
Joe M. Martinez BS, SCT (ASCP)
Cytopathology Supervisor
Audie Murphy VA Hospital
San Antonio, TX
Slide 1: Adenoid cystic carcinoma.
Extracellular hyaline globules.
Slide 2: Maliganant cells arranged
around pseudoglandular or microcystic
spaces which appear clear in H& E.
The Texas Society of Cytology
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